Presentation Type
Panel Discussion
Start Date
12-3-2022 11:45 AM
End Date
12-3-2022 12:45 PM
Abstract
Salvia officinalis or Sage (The “Salvation Plant”) is known to have various health benefits. Salvia officinalis has been known to treat menstrual cycle pains, gastroenteritis problems, improve liver function, as well as in applications for anticancer remedies and neurodegenerative diseases. This fragrant plant is most often found in the Mediterranean, Southeast Asia, and South America. This research aims to test the raw and vinegar-baked medicinal plant to investigate the change in its chemistry and its biological effect. The plant was purchased as dry leaves and stems. It was then grounded and extracted. The extractions were done via a Soxhlet extraction (SE) using Ethanol solvent. Different steps of liquid-liquid partitions will be realized before proceeding to normal-phase chromatography (NP). The samples will be subjected to high performance liquid-phase chromatography coupled with mass spectroscopy (HPLC-MS) to investigate further, any new secondary metabolites. Three replicates of each extract are being tested for their antibacterial effect against a panel of positive (+) and gram negative (-) bacteria.
Keywords
Salvia, Secondary Metabolites, antibacterial
Included in
Chemical and Pharmacologic Phenomena Commons, Medicinal and Pharmaceutical Chemistry Commons, Natural Products Chemistry and Pharmacognosy Commons
Arkansas Women in STEM Conference Presentation: Investigations of Salvia officinalis Secondary Metabolites
Salvia officinalis or Sage (The “Salvation Plant”) is known to have various health benefits. Salvia officinalis has been known to treat menstrual cycle pains, gastroenteritis problems, improve liver function, as well as in applications for anticancer remedies and neurodegenerative diseases. This fragrant plant is most often found in the Mediterranean, Southeast Asia, and South America. This research aims to test the raw and vinegar-baked medicinal plant to investigate the change in its chemistry and its biological effect. The plant was purchased as dry leaves and stems. It was then grounded and extracted. The extractions were done via a Soxhlet extraction (SE) using Ethanol solvent. Different steps of liquid-liquid partitions will be realized before proceeding to normal-phase chromatography (NP). The samples will be subjected to high performance liquid-phase chromatography coupled with mass spectroscopy (HPLC-MS) to investigate further, any new secondary metabolites. Three replicates of each extract are being tested for their antibacterial effect against a panel of positive (+) and gram negative (-) bacteria.