Presentation Type
Poster
Department
Biology
Location
Walker Conference Center B
Description
Photodynamic therapy (PDT) is a treatment method for various illnesses including cancer that uses a special drug, called a photosensitizer (PS). When a patient is injected with a PS, over time the PS is absorbed by the cancerous tumor. Light is then applied to area for treatment. The light then causes the drug to be activated, and singlet oxygen is produced that kills the cells. The PS in partnership with light causes cancer cells to undergo apoptosis. This research focuses on testing three novel water-soluble porphyrins, ZnTPPEA, H2TPP – TRIS, and H2TPPADIPA, as potential photosensitizing agents. All three novel photosensitizing agents were tested on the A549 human lung carcinoma cell line using MTT assays to determine cell viability using red light, white light, and dark conditions.
Creative Commons License
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Included in
Investigating Three novel Porphyrins for the Possible Treatment for Lung Cancer Using Red and White Light
Walker Conference Center B
Photodynamic therapy (PDT) is a treatment method for various illnesses including cancer that uses a special drug, called a photosensitizer (PS). When a patient is injected with a PS, over time the PS is absorbed by the cancerous tumor. Light is then applied to area for treatment. The light then causes the drug to be activated, and singlet oxygen is produced that kills the cells. The PS in partnership with light causes cancer cells to undergo apoptosis. This research focuses on testing three novel water-soluble porphyrins, ZnTPPEA, H2TPP – TRIS, and H2TPPADIPA, as potential photosensitizing agents. All three novel photosensitizing agents were tested on the A549 human lung carcinoma cell line using MTT assays to determine cell viability using red light, white light, and dark conditions.