Comparing Degradation Rates of Polyesters Towards a Novel Degradable Polymer

Date of Award

5-7-2024

Document Type

Thesis

Department

Chemistry

First Reader

Dr. Sharon Hamilton

Second Reader

Dr. Sara Hubbard

Third Reader

Professor Jennifer Pittman

Abstract

Polymers have been used for a variety of biomedical applications, and polyesters specifically have significant use as biodegradable tools. Dr. Hamilton’s research team has been investigating biomimetic poly(ɛ-caprolactone) and poly(δ-valerolactone) (PCL and PDVL) in order to create a better wound dressing that would degrade as the body heals. In lab, commercial ɛ-caprolactone and δ-valerolactone underwent ester modifications as a step to synthesize biomimetic PCL and PDVL. A degradation study was also performed on PCL and PDVL in order to analyze how their degradation rates differ.

Comments

This thesis is currently embargoed. It will be available May 2029.

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