Date of Award
2008
Document Type
Thesis
Department
Biology
First Reader
Dr. Lori Hensley
Second Reader
Dr. Martin D. "Marty" Perry
Third Reader
Dr. Scott Jackson
Abstract
Multiple Sclerosis (MS) is a neurodegenerative disease that is estimated to affect 400,000 Americans. There is no cure for MS and some treatments at this point are toxic to patients. Dr. Lori Hensley's lab is researching two drugs that could potentially be used to treat MS without toxic effects. Previous work in the lab shows ajulemic acid, a synthetic molecule similar to metabolites from the cannabis plant, selectively suppresses markers of the inflammatory response. worked on the mechanism of ajulemic acid's action by investigating the roles of several candidate receptors in mediating these observed effects.
Recommended Citation
Lemons, Natalie Shea, "Cannabinoid Modulation of Microglial Activation in Multiple Sclerosis" (2008). Honors Theses. 59.
https://scholarlycommons.obu.edu/honors_theses/59