Patterns of Autism Spectrum Symptomatology in Individuals with Down Syndrome without Comorbid Autism Spectrum Disorder
Document Type
Article
Publication Date
1-2015
Abstract
Background: Prevalence estimates of autism spectrum disorder (ASD) in Down syndrome (DS) are highly varied. This variation is partly due to the difficulty of screening for and diagnosing comorbid ASD in individuals with a syndrome that carries its own set of social communicative and behavioral difficulties that are not well documented. The aim of this study was to identify the typical range of social communicative impairments observed in children, adolescents, and young adults with DS who do not have comorbid ASD.
Methods: We examined patterns of scores from the five subscales of the Social Responsiveness Scale (SRS) in 46 individuals with DS (ages 10–21 years) without comorbid ASD relative to the published normative sample. We also explored the correlations between SRS symptomatology and age, nonverbal cognition, and receptive language.
Results: SRS scores were elevated (i.e., more ASD symptoms endorsed), with mean scores falling into the clinically significant range. Analysis by subscale revealed a specific pattern, with Autistic Mannerisms and Social Cognition scores significantly more elevated than Social Communication scores, which were significantly more elevated than Social Awareness and Social Motivation scores. Correlations between SRS scores and the other measures varied by subscale.
Conclusions: General elevated ASD symptomatology on the SRS indicates the need for developing populationbased norms specific to DS. The pattern of scores across subscales should inform clinicians of the typical range of behaviors observed in DS so that individuals with atypical patterns of behavior can be more easily identified and considered for a full ASD evaluation.
Publication Title
Journal of Neurodevelopmental Disorders
Publisher Statement
Copyright Journal of Neurodevelopmental Disorders 2015
Creative Commons License: https://creativecommons.org/licenses/by/4.0/legalcode
DOI
https://doi.org/10.1186/1866-1955-7-5
Recommended Citation
Channell, Marie Moore; Phillips, B. Allyson; Loveall, Susan J.; Conners, Frances A.; Bussanich, Paige M.; and Klinger, Laura Grofer, "Patterns of Autism Spectrum Symptomatology in Individuals with Down Syndrome without Comorbid Autism Spectrum Disorder" (2015). Articles. 122.
https://scholarlycommons.obu.edu/articles/122
Patterns of Autism Spectrum Symptomatology File