Presenter Educational Level

undergraduate

Department

Biology

Presentation Type

Panel Discussion

Start Date

20-3-2021 11:30 AM

Abstract

Malaria is a disease that disproportionately affects several third world countries. It is a life-threatening illness that is transmitted by mosquitoes that act as vesicles for parasites. The parasites cause a febrile illness in those that are not immune. Children under five are most susceptible to the disease which can lead to multi-organ failure and death. The disease is preventable and curable, but according to the world health organization, countries disproportionately affected cannot afford these preventative care measures or have developed resistance to treatments. Therefore it would be advantageous to develop a new treatment for malaria that focuses on cost effectiveness and something that is new to combat resistance to current treatments. A favorable drug might feature an antibiotic component as well as salicylamide. The antibiotic would combat the disease similar to the antibiotics used to treat now like Doxycycline. The salicylamide component would be beneficial because it could act as an analgesic as well as prevent coagulation and clotting commonly caused by malaria. In the following experiments, reactions and compounds were created in order to achieve a compound with two benzene rings which would make up one half of the drug.

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Mar 20th, 11:30 AM

Synthesis of N-Benzoyl-2-hydroxybenzamides as Agents Utilized in Treatment of Malaria

Malaria is a disease that disproportionately affects several third world countries. It is a life-threatening illness that is transmitted by mosquitoes that act as vesicles for parasites. The parasites cause a febrile illness in those that are not immune. Children under five are most susceptible to the disease which can lead to multi-organ failure and death. The disease is preventable and curable, but according to the world health organization, countries disproportionately affected cannot afford these preventative care measures or have developed resistance to treatments. Therefore it would be advantageous to develop a new treatment for malaria that focuses on cost effectiveness and something that is new to combat resistance to current treatments. A favorable drug might feature an antibiotic component as well as salicylamide. The antibiotic would combat the disease similar to the antibiotics used to treat now like Doxycycline. The salicylamide component would be beneficial because it could act as an analgesic as well as prevent coagulation and clotting commonly caused by malaria. In the following experiments, reactions and compounds were created in order to achieve a compound with two benzene rings which would make up one half of the drug.