Acute Ingestion of a Ketone Ester Beverage and Its Impact Upon Glycaemic Control, Appetite, and Food Intake

Acute Ingestion of a Ketone Ester Beverage and Its Impact Upon Glycaemic Control, Appetite, and Food Intake

Ketosis is a state in which ketone bodies are hepatically produced, which can lead to weight loss, appetite suppression, and improved glycaemic control. Reaching a state of ketosis can be difficult to attain and can be induced by fasting or restricting dietary carbohydrates. Exogenous ketones in the form of ketone monoesters have been shown to efficiently induce a state of ketosis. Ketone monoesters are synthetic molecules. The aim of the study was to determine the impact of the acute ingestion of a ketone ester beverage upon appetite, food intake, and glycaemic control. Participants ingested the ketone ester beverage and measurements were taken to gauge perceived appetite, food intake, related peripheral hormones, glycaemic control, and blood ketone levels. The results of the study showed that the ketone monoester beverage caused an increase in blood ketone levels and resulted in appetite suppression and improved glycaemic control. The ingestion of a ketone ester beverage may offer therapeutic use for the prevention and treatment of chronic, nutritionally mediated diseases, such as obesity and Type 2 diabetes.