Date of Award

2008

Document Type

Thesis

Department

Biology

First Advisor

Dr. Lori Hensley

Second Advisor

Dr. Marty Perry

Third Advisor

Dr. Scott Jackson

Abstract

Multiple Sclerosis (MS) is a neurodegenerative disease that is estimated to affect 400,000 Americans. There is no cure for MS and some treatments at this point are toxic to patients. Dr. Lori Hensley's lab is researching two drugs that could potentially be used to treat MS without toxic effects. Previous work in the lab shows ajulemic acid, a synthetic molecule similar to metabolites from the cannabis plant, selectively suppresses markers of the inflammatory response. worked on the mechanism of ajulemic acid's action by investigating the roles of several candidate receptors in mediating these observed effects.

Included in

Diseases Commons

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